SDHB Polyclonal Antibody
Price:
Size:
100μL
50μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human liver,Human kidney |
Dilution | IHC 1:75-1:150 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant Human SDHB protein expressed by E.coli |
Abbre | SDHB |
Synonyms | CWS2; DHSB; Ip; Iron sulfur subunit; Iron sulfur subunit of complex II; Iron-sulfur subunit of complex II; mitochondrial; PGL 4; PGL4; SDH 1; SDH; SDH1; SDH2; SDH2; homolog of; SdhB; SDHIP; Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial; Succinate dehydrogenase [ubiquinone] iron sulfur subunit; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit; succinate dehydrogenase [ubiquinone] iron-sulfur subunit; mitochondrial; Succinate Dehydrogenase 1 Iron Sulfur Subunit; Succinate Dehydrogenase 2; S. cerevisiae; homolog of; Succinate dehydrogenase complex iron sulfur subunit B; Succinate dehydrogenase complex subunit B iron sulfur; Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein; succinate dehydrogenase complex; subunit B; iron sulfur (Ip); Succinate dehydrogenase iron sulfur protein |
Swissprot | |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH 7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cell Biology; Metabolism; Signal Transduction |
Conjugation | Unconjugated |
Background | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. |
Immunohistochemistry of paraffin-embedded Human liver using SDHB Polyclonal Antibody at dilution of 1:150
Immunohistochemistry of paraffin-embedded Human kidney using SDHB Polyclonal Antibody at dilution of 1:150
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