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SETMAR Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human esophagus cancer
Dilution
IHC 1:50-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human SETMAR
Abbre
SETMAR
Synonyms
Histone lysine N methyltransferase;Histone lysine N methyltransferase SETMAR;Hsmar 1;Hsmar1;Mariner transposase Hsmar1;Metnase;SET domain and mariner transposase fusion;SET domain and mariner transposase fusion gene;SET domain and mariner transposase fusion gene containing protein;SET domain and mariner transposase fusion gene-containing protein;Setmar;SETMR抗体
Swissprot
Cellular Localization
Nucleus. Chromosome.
Concentration
1.08 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using SETMAR Polyclonal Antibody at dilution of 1:60(×200)


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