TMED10 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human; Mouse; Rat
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB:Mouse pancreas,Mouse Pancreas,Rat lung,Mouse liver,Hela,Raji Verified Samples in IHC:Human lung cancer,Human liver cancer |
Dilution | WB 1:1000-1:5000;IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Fusion protein of human TMED10 |
Abbre | TMED10 |
Synonyms | 1110014C03Rik ;21 kDa transmembrane trafficking protein;21 kDa transmembrane-trafficking protein;MGC102351;p23;p24 family protein delta 1;p24 family protein delta-1;p24(DELTA);p24delta;p24delta1;S31I125;S31III125;TMED 10;Tmed10;TMEDA;Tmp 21 I;Tmp 21;Tmp 21 I;Tmp-21-I;Transmembrane emp24 domain containing protein 10;Transmembrane emp24 domain-containing protein 10;Transmembrane emp24-like trafficking protein 10 (yeast);Transmembrane protein Tmp21;Transmembrane trafficking protein 21kD抗体 |
Swissprot | |
Calculated MW | 25 kDa |
Observed MW | Refer to figures |
Cellular Localization | Golgi apparatus>cis-Golgi network membrane. Melanosome. Endoplasmic reticulum membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane. Cytoplasmic vesicle>secretory vesicle membrane. Cell membrane. Golgi apparatus>trans-Golgi network membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Cycles between compartments of the early secretatory pathway. |
Concentration | 1.14 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Neuroscience; Signal transduction |
Conjugation | Unconjugated |
Background | This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. |
Western blot analysis of NIH/3T3 cell Mouse Pancreas tissue Rat lung tissue Mouse liver tissue Hela Raji cell lysates using TMED10 Polyclonal Antibody at dilution of 1:900
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TMED10 Polyclonal Antibody at dilution of 1:65(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TMED10 Polyclonal Antibody at dilution of 1:65(×200)
E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |