UMOD Polyclonal Antibody
Price:
Size:
100μL
50μL
- 宿主： Rabbit
- 反应性： Human
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human kidney |
| Dilution | IHC 1:100-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Human UMOD protein expressed by E.coli |
| Abbre | UMOD |
| Synonyms | ADMCKD2;FJHN;HNFJ;HNFJ1;MCKD2;medullary cystic kidney disease 2 (autosomal dominant);Tamm Horsfall glycoprotein;Tamm Horsfall urinary glycoprotein;Tamm-Horsfall urinary glycoprotein;THGP;THP;Umod;Urehd1;urehr4;UROM_HUMAN;uromodulin (uromucoid; Tamm-Horsfall glycoprotein);
Uromodulin |
| Swissprot | |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH 7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Cell Biology |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. |
Immunohistochemistry of paraffin-embedded Human kidney using UMOD Polyclonal Antibody at dilution of 1:200
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
