UMOD Polyclonal Antibody
Price:
Size:
100 μL
25 μL
- 宿主： Rabbit
- 反应性： Human
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC: Human kidney |
| Dilution | IHC 1:100-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Human UMOD protein expressed by E.coli |
| Abbre | UMOD |
| Synonyms | Tamm-Horsfa, ADMCKD2, FJHN, HNFJ, HNFJ1, MCKD2, THGP, THP, Tamm Horsfall glycoprotein, Tamm Horsfall urinary glycoprotein, Tamm-Horsfall urinary glycoprotein, UROM_HUMAN, Umod, Urehd1, medullary cystic kidney disease 2 (autosomal dominant), urehr4, uromodulin (uromucoid |
| Swissprot | |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. |
Immunohistochemistry of paraffin-embedded Human kidney using UMOD Polyclonal Antibody at dilution of 1:200
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500 μL , 120 μL , 1 mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 50 mL , 18 mL , 6 mL , 3 mL |
| E-IR-R220 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50 Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |
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