请输入货号/产品关键词 !
插入特殊字符:
  • α
  • β
  • γ
  • δ
  • ε
  • ζ
  • η
  • θ
  • κ
  • μ
  • ω
  • σ
  • τ
  • λ
  • ⅩⅢ
  • ⅩⅢ
  • ⅩⅣ
  • ⅩⅤ
  • ⅩⅦ
  • ⅩⅧ
  • 收起 ↑
热门搜索: 最新活动 文献引用 新品速递 一步法ELISA 流式抗体 铜死亡 Annexin V凋亡检测 TUNEL凋亡检测 未包被ELISA 铁死亡 双硫死亡

UNC13B Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer,Human lung cancer
Dilution
IHC 1:50-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human UNC13B
Abbre
UNC13B
Synonyms
hmunc13;MGC133279;MGC133280;munc13;Munc13-2;Protein unc-13 homolog B;UN13B;unc-13 homolog B (C. elegans);UNC13;Unc13b;Unc13h2抗体
Swissprot
Cellular Localization
Cytoplasm. Membrane. Cell membrane. Cell junction>synapse. Localized to synapses. Translocated to the plasma membrane in response to phorbol ester binding.
Concentration
1.5 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Neuroscience; Signal transduction
Conjugation
Unconjugated
Background
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using UNC13B Polyclonal Antibody at dilution of 1:85(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using UNC13B Polyclonal Antibody at dilution of 1:85(×200)


微信客服 微信客服 在线留言 TOP