UNC13B Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human; Mouse; Rat
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human liver cancer,Human lung cancer |
Dilution | IHC 1:50-1:300 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Fusion protein of human UNC13B |
Abbre | UNC13B |
Synonyms | hmunc13;MGC133279;MGC133280;munc13;Munc13-2;Protein unc-13 homolog B;UN13B;unc-13 homolog B (C. elegans);UNC13;Unc13b;Unc13h2抗体 |
Swissprot | |
Cellular Localization | Cytoplasm. Membrane. Cell membrane. Cell junction>synapse. Localized to synapses. Translocated to the plasma membrane in response to phorbol ester binding. |
Concentration | 1.5 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Neuroscience; Signal transduction |
Conjugation | Unconjugated |
Background | This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. |
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using UNC13B Polyclonal Antibody at dilution of 1:85(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using UNC13B Polyclonal Antibody at dilution of 1:85(×200)
E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |