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WISP2 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human tonsil,Human cervical cancer
Dilution
IHC 1:30-1:150
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human WISP2
Abbre
WISP2
Synonyms
CCN family member 5;CCN5;Connective tissue growth factor like protein;Connective tissue growth factor related protein 58;Connective tissue growth factor-like protein;Connective tissue growth factor-related protein 58;CT58;CTGF L;CTGF-L;WISP 2;WISP-2;Wisp2;WISP2;Wnt 1 signaling pathway protein 2;WNT1 inducible signaling pathway protein 2;WNT1-inducible-signaling pathway protein 2
Swissprot
Cellular Localization
Secreted.
Concentration
0.8 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Cardiovascular; Stem Cells
Conjugation
Unconjugated
Background
This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
Immunohistochemistry of paraffin-embedded Human tonsil tissue using WISP2 Polyclonal Antibody at dilution of 1:45(×200)
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using WISP2 Polyclonal Antibody at dilution of 1:45(×200)


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