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WNK4 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human colorectal cancer
Dilution
IHC 1:40-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human WNK4
Abbre
WNK4
Synonyms
PHA 2B;PHA2B;PRKWNK 4;PRKWNK4;Protein kinase lysine deficient 4;Protein kinase lysine-deficient 4;Protein kinase with no lysine 4;Serine/threonine protein kinase WNK4;Serine/threonine-protein kinase WNK4;WNK lysine deficient protein kinase 4;Wnk4;WNK4
Swissprot
Cellular Localization
Cell junction, tight junction. Present exclusively in intercellular junctions in the distal convoluted tubule and in both the cytoplasm and intercellular junctions in the cortical collecting duct. WNK4 is part of the tight junction complex (By similarity).
Concentration
1.32 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Signal transduction
Conjugation
Unconjugated
Background
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissueusing WNK4 Polyclonal Antibody at dilution of 1:45(×200)


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