ZBTB10 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB:Jurkat Verified Samples in IHC:Human colorectal cancer,Human tonsil |
Dilution | WB 1:500-1:2000;IHC 1:50-1:300 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human ZBTB10 |
Abbre | ZBTB10 |
Synonyms | FLJ12752;OTTHUMP00000207119;RINZF;RINZFC;ZBT10;ZBTB10;Zinc finger and BTB domain containing protein 10;Zinc finger and BTB domain-containing protein 10;Zinc finger protein RIN ZF |
Swissprot | |
Calculated MW | 95 kDa |
Observed MW | Refer to figures |
Cellular Localization | Nucleus. |
Concentration | 1.7 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Background | RINZF, also known as ZBTB10 (zinc finger and BTB domain containing protein 10), is a 847 amino acid protein that contains one BTB/POZ domain and two C2H2-type zinc fingers. Localized to the nucleus, RINZF is believed to play a role in transcriptional regulation. Specifically, RINZF is capable of binding to the CACC element of the Gastrin promoter. In this regard, RINZF competes with Sp1 for CACC binding and interferes with Sp1 transactivation, thereby regulating Gastrin gene expression. The rat RINZF protein shares 98% homology with the human RINZF protein, suggesting that RINZF is a conserved protein. Due to alternative splicing events, two RINZF isoforms exist. In addition, RINZF may be phosphorylated by ATR or ATM upon DNA damage. |
Western blot analysis of Jurkat cell lysateusing ZBTB10 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissueusing ZBTB10 Polyclonal Antibody at dilution of 1:100(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissueusing ZBTB10 Polyclonal Antibody at dilution of 1:100(×200)
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E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |