HAO1 Monoclonal Antibody

货号：E-AB-22108
说明书

Price: ¥2310 ¥1420 ¥580

Size:

120μL 60μL 20μL

宿主： Mouse
反应性： Mouse;Rat
应用性： WB;IHC-p;IF

Verified Samples	Verified Samples in WB:Mouse liver,Rat liver Verified Samples in IHC:Human liver Verified Samples in IF:Human appendix
Dilution	WB 1:500-1:2000;IHC 1:50-1:300;IF 1:100-1:300
Clonality	Monoclonal
Isotype	IgG
Immunogen	Recombinant Protein
Abbre	HAO1
Synonyms	(S) 2 hydroxy acid oxidase;Glycolate oxidase;GOX;GOX1;HAO1;HAOX1;HAOX1;Hydroxyacid oxidase 1;MGC142225;MGC142227;OTTHUMP00000030231抗体
Swissprot	Q9UJM8
Observed MW	41kDa
Cellular Localization	Peroxisome.
Tissue Specificity	Liver.
Concentration	1 mg/mL
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method	Protein A purification
Research Areas	Cardiovascular; Metabolism; Signal Transduction
Clone No.	Clone:3B2
Conjugation	Unconjugated
Background	This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. HAO1 (Hydroxyacid Oxidase 1) is a Protein Coding gene. Diseases associated with HAO1 include Lactocele and Primary Hyperoxaluria. Among its related pathways are Glyoxylate metabolism and glycine degradation and Peroxisome. GO annotations related to this gene include receptor binding and FMN binding. An important paralog of this gene is HAO2.

Western Blot analysis of 1) Mouse liver, 2) Rat liver with HAO1 Monoclonal Antibody.

Immunohistochemistry of paraffin-embedded Human liver tissue using HAO1 Monoclonal Antibody at dilution of 1:200.

Immunofluorescence analysis of Human appendix tissue using HAO1 Monoclonal Antibody at dilution of 1:200.

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