MICU1 Monoclonal Antibody
Price:
Size:
120μL
60μL
20μL
- 宿主： Mouse
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC-p;IF
| Verified Samples |
Verified Samples in WB:MCF-7,Mouse brain,Rat brain Verified Samples in IHC:Mouse testis Verified Samples in IF:Human appendix |
| Dilution | WB 1:500-1:2000;IHC 1:100-1:200;IF 1:100-1:300 |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Recombinant Protein |
| Abbre | MICU1 |
| Synonyms | Allergen Hom s 4;ara CALC;atopy related autoantigen;atopy related autoantigen CALC;Atopy-related autoantigen CALC;CALC;calcium binding atopy related autoantigen 1;Calcium uptake protein 1;calcium uptake protein 1;mitochondrial;Calcium-binding atopy-related autoantigen 1;CBARA1;EFHA3;FLJ12684;MICU1;MICU1;mitochondrial;mitochondrial calcium uptake 1;MPXPS抗体 |
| Swissprot | |
| Observed MW | 55kDa |
| Cellular Localization | Mitochondrion inner membrane. |
| Tissue Specificity | Expressed in epithelial cell line. Strongly expressed in epidermal keratinocytes and dermal endothelial cells. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Purification Method | Protein A purification |
| Research Areas | Cancer; Metabolism; Immunology; Signal Transduction |
| Clone No. | Clone:4E7 |
| Conjugation | Unconjugated |
| Background | This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3. |
Western Blot analysis of 1) MCF7, 2) Mouse brain, 3) Rat brain with MICU1 Monoclonal Antibody.
Immunohistochemistry of paraffin-embedded Mouse testis tissue using MICU1 Monoclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Human appendix tissue using MICU1 Monoclonal Antibody at dilution of 1:200.
