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CASP4 Polyclonal Antibody

CASP4 Polyclonal Antibody
  • CASP4 Polyclonal Antibody
  • CASP4 Polyclonal Antibody
  • CASP4 Polyclonal Antibody
  • CASP4 Polyclonal Antibody

Price: ¥2100.00 ¥800.00

Size:
100 μL 25 μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse
  • 应用性: IHC;IF
Verified Samples
Verified Samples in IHC: Human tonsil, Human colon
Verified Samples in IF: Mouse NIH-3T3
Dilution
IHC 1:400-1:800, IF 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Human CASP4 protein expressed by E.coli
Abbre
CASP4
Synonyms
Apoptotic cysteine protease Mih1/TX, CASP-4, CASP4, Caspase 4 apoptosis related cysteine peptidase, Caspase-4 subunit 2, Caspase4, ICE(rel)-II, ICE(rel)II, ICEREL II, ICH2, Mih1/TX, Protease ICH-2, Protease TX, TX
Swissprot
Cellular Localization
Cytosol, AIM2 inflammasome complex, cytosol, IPAF inflammasome complex, NLRP3 inflammasome complex, Endoplasmic reticulum, endoplasmic reticulum, endoplasmic reticulum membrane, Extracellular region or secreted, extracellular region, Mitochondrion, Plasma Membrane, Other locations: protein complex.
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method
Antigen Affinity Purification
Research Areas
Cancer, Cell Biology, Metabolism
Conjugation
Unconjugated
Background
This gene encodes a member of the cysteine proteases that plays important roles in apoptosis,cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4,apoptosis-related cysteine peptidase",this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.
Immunohistochemistry of paraffinembedded Human tonsil using CASP4 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffinembedded Human colon cancer using CASP4 Polyclonal Antibody at dilution of 1:800
Immunofluorescence analysis of NIH-3T3 cells using CASP4 Polyclonal Antibody at dilution of 1:200
E-AB-1003 Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1010 Goat Anti-Rabbit IgG(H+L)(Cyanine3 conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1014 Goat Anti-Rabbit IgG(H+L)(FITC conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1060 Goat Anti-Rabbit IgG(H+L)(Elab Fluor® 594 conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1075 Goat Anti-Rabbit IgG(H+L)(Elab Fluor® 647 conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1099 Elab Fluor® Violet 450-Goat Anti-Rabbit IgG(H+L) 500 μL , 120 μL , 1 mL
E-AB-1194 HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed 500 μL , 120 μL , 1 mL
E-IR-R217 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) 50 mL , 18 mL , 6 mL , 3 mL
E-IR-R220 Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) 10mL , 3mL
E-IR-R221 Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) 10mL , 3mL
E-IR-R304A Western Blot Detection Kit 50 Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50 Assays


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