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CYCS Polyclonal Antibody

Price: ¥3300 ¥2220 ¥1380

Size:
200μL 120μL 60μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB;IHC;IF
Verified Samples
Verified Samples in WB:Hela,HepG2,Mouse lung,Mouse brain,Rat brain
Verified Samples in IHC:Human lung cancer,Human heart
Verified Samples in IF:Mouse kidney,Mouse liver
Dilution
WB 1:500-1:2000;IHC 1:500-1:1000;IF 1:200-1:800
Clonality
Polyclonal
Isotype
IgG
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome c
Abbre
CYCS
Synonyms
Cytochrome C; Somatic;CYC;Cytochrome C;THC4;HCS.抗体
Swissprot
Calculated MW
12kDa
Observed MW
12kDa
Cellular Localization
Mitochondrion
Concentration
1.5 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cell Biology; Cardiovascular; Metabolism; Signal Transduction
Conjugation
Unconjugated
Background
Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation,cytochrome c can be released from mitochondria into cytoplasm,resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition,cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
Western Blot analysis of various samples using CYCS Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded human lung cancer using CYCS Polyclonal Antibody at dilution of 1:1000.
Immunofluorescence analysis of paraffin-embedded mouse kidney using CYCS Polyclonal Antibody at dilution of 1:500.
Immunofluorescence analysis of paraffin-embedded mouse liver using CYCS Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded Human Heart using CYCS Polyclonal Antibody(Elabscience Product Detected by Lifespan).
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