(KO Validated) HuR / ELAVL1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC;IF
| Verified Samples |
Verified Samples in WB:U-251MG,293T,HeLa,Jurkat,K562,PC-3 Verified Samples in IHC:Mouse testis,Mouse kidney,Rat testis,Human kidney cancer,Human esophageal cancer Verified Samples in IF:MCF-7 |
| Dilution | WB 1:500-1:2000;IHC 1:100-1:200;IF 1:50-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant fusion protein of human HuR / ELAVL1 (NP_001410.2). |
| Abbre | HuR / ELAVL1 |
| Synonyms | ELAV1;HUR;Hua;MelG;HuR / ELAVL1;ELAVL1抗体 |
| Swissprot | |
| Calculated MW | 36kDa/38kDa |
| Observed MW | 37kDa |
| Cellular Localization | Cytoplasm. |
| Concentration | 1mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. |
Western blot analysis of extracts of various cell lines using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts from normal (control) and HuR / ELAVL1 knockout (KO) 293T cells using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Mouse testis using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse kidney using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Rat testis using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Human kidney cancer using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunofluorescence analysis of MCF-7 cells using HuR / ELAVL1 Polyclonal Antibody
